Canada Goose Parka An Unconventional Treatment for Depression
canada goose black friday sale I watched a good ‘psychological thriller’ the other night Side Effects by Steven Soderbergh that centers on a woman’s debilitating depression and critiques canada goose coats on sale the pharmaceutical industry’s untoward influence over clinicians (it turns into a plot twisty crime thriller, but that’s beside the point). The film Canada Goose Outlet got me thinking canada goose clearance sale about our reliance on psychotropic medications to treat psychological distress, and how helpless we are when these pills don’t work.
Canada Goose Outlet I’ve written before on the over medicalization of Canada Goose Parka psychiatric disorders and the pharmaceutical industry’s role in this controversy, but this time the topic got me thinking about possible alternative treatments for depression, other than cognitive behavioral therapy or mood altering medications.
canada goose clearance One innovative method for treating depression that has received canada goose factory sale attention is sleep deprivation. Acute sleep deprivation has been canada goose black friday sale touted as having a 60% success rate in immediate relief from depression; however, this effect is temporary, only lasting until you finally do nod off.
canada goose clearance sale At first this might seem surprising, after all, think about how cranky and irritable you feel after a poor night of Canada Goose Jackets sleep. missing an entire night’s sleep, or more than 12 hours) can actually have the opposite effect. Remember that loopy, giggly, hysterical feeling you used to uk canada goose outlet get staying up all night at a sleepover, or at 5am in the library while studying for exams? It is believed canadian goose jacket that this phenomenon is at least partially caused by an alteration in activation and connectivity in our frontal canada goose uk shop cortex, potentially offsetting the harmful effects chronic depression can have on this area.
Canada Goose sale It Canada Goose Coats On Sale is still relatively unknown how or why exactly this works though. A recent canada goose study from canada goose coats Tuft’s University attempted to answer this question by testing sleep deprivation and its efficacy as cheap canada goose uk an anti depressant in depressed mice. First, researchers confirmed that depressed animals who were sleep deprived for 12 hours displayed significantly less depressive symptoms than control depressed mice. Then, for the first time, they were able to link this buy canada goose jacket cheap effect to the activation of a certain type of brain cell, astrocytes, that release a particular protein, adenosine.
buy canada goose jacket Adenosine is important in sleep regulation, and its absence has also been implicated in a greater risk for depression. Adenosine release is increased the longer you’re canada goose store awake (to a point), making you feel less aroused and more tired, and acting as part of your normal sleep wake cycle. A beneficial side effect of its release now also appears to be an alleviation of depressive symptoms. However, after 72 hours of sleep deprivation there was no change in adenosine levels, as the astrocyte cells had largely shut down by this point. Thus, there was canada goose uk black friday no effect of more extreme canada goose outlet sleep deprivation on feelings of depression. Also, as soon as you do catch up on some zzz’s your adenosine levels return to normal and the anti depressant effects disappear.
buy canada goose jacket cheap Adenosine’s effect on depression potentially works by altering the electrical signals in your brain, causing an immediate change in mood and behavior. Other fast acting, unconventional treatments for depression, like deep brain stimulation and electro shock therapy, are Canada Goose Online thought to work in Canada Goose online a similar manner, impacting the brain’s electrical currents. These treatments also last much uk canada goose longer, suggesting that there may be a way to canada goose clearance channel adenosine’s electrical effect into a longer term solution.
canada goose store I should be clear that I am in no way against using psychotropic medication to treat psychiatric disorders; in fact, in many instances these pills are absolutely essential. But in cases where these medications don’t work, or where their Side Effects are too severe (seriously, go see the movie!), it is important to have well researched Canada Goose sale alternatives to the standard course of treatment. Sleep deprivation in depression. canada goose uk outlet Expert Review of Neurotherapeutics 10 1101 1115 (2010).
canada goose coats Hines DJ et al. Antidepressant effects of sleep deprivation require astrocyte dependent adenosine mediated signaling. Translational Psychiatry 3, e212 (2013).
cheap Canada Goose Image credit: Tom Varco and Bruno Pascal (via Wikimedia Commons)
canada goose deals Excellent point, Jordan. I’ve wondered about the risks of sleep deprivation therapy as well. I don’t know of cheap Canada Goose anyone who actually “prescribes” this, as the effects disappear as soon as the patient gets some sleep. And in the Translational Psych paper it appears the effects only work with minimal sleep deprivation, not after two nights because the cells seemingly shut down at that point. I think the question is instead how can you use this knowledge? Because sleep deprivation does temporarily alleviate symptoms, and knowing that hypersomnia is a common symptom of depression, is there a similar alternative mechanism you could tap into? From these results, it appears that adenosine, and its effect on delta wave activity, might be behind the effect and a potential target for future research. driving) not to mention, buy canada goose jacket how chronic versus short term sleep deprivation affects depression. Naturally, depressed people sleep more than non depressed, and are sleepier during https://www.canadagoosesale.biz the day. Given that, how reasonable a treatment do you think this could be in the “real world”.